Returns Chart

Janus Henderson Global Life Sciences Fund S (JFNSX) Total Return
Created with Highcharts 11.1.0Jul '24Oct '24Jan '25Apr '250.00%-8.87%

Key Stats

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Net Expense Ratio Total Assets Under Management Weighted Average Dividend Yield Turnover Ratio (Generic)
1.18% 4.655B 1.14% 35.00%
1 Year Fund Level Flows 1 Year Total Returns (Daily) Annualized Total Returns Since Inception (Daily) Max Drawdown (Since Inception)
-487.49M -8.87% Upgrade Upgrade

Basic Info

Investment Strategy
The Fund seeks long-term growth of capital. The Fund invests, under normal circumstances, at least 80% of its net assets in securities of companies that the portfolio managers believe have a life science orientation. The Fund normally invests in issuers from several different countries, which may include United States.
General
Security Type Mutual Fund
Broad Asset Class Sector Equity
Broad Category Equity
Global Peer Group Equity Sector Healthcare
Peer Group Global Health/Biotechnology Funds
Global Macro Equity Industry Sector
US Macro World Sector Equity Funds
YCharts Categorization --
YCharts Benchmark --
Prospectus Objective Global Health/Biotechnology Funds
Fund Owner Firm Name Janus Henderson Investors
Broad Asset Class Benchmark Index
^MSWNTR 100.0%

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Net Fund Flows Versus Peer Group

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1M
3M
6M
YTD
1Y
3Y
5Y
10Y
 
80.00B
60.00B
40.00B
20.00B
0
-20.00B
1 Month
% Rank: 90
-601.72M Peer Group Low
1.261M Peer Group High
1 Year
% Rank: 90
-487.49M
-5.812B Peer Group Low
79.00M Peer Group High
3 Months
% Rank: 90
-1.623B Peer Group Low
129.85M Peer Group High
3 Years
% Rank: 90
-12.56B Peer Group Low
164.87M Peer Group High
6 Months
% Rank: 90
-3.907B Peer Group Low
22.73M Peer Group High
5 Years
% Rank: 90
-20.03B Peer Group Low
703.21M Peer Group High
YTD
% Rank: 90
-2.403B Peer Group Low
72.21M Peer Group High
10 Years
% Rank: 90
-37.52B Peer Group Low
615.98M Peer Group High
Date Unavailable

Performance Versus Peer Group

 
20%
15%
10%
5%
0
Name
1M
3M
YTD
1Y
3Y
5Y
10Y
15Y
Total Return (NAV)
12.00%
12.00%
12.00%
12.00%
12.00%
12.00%
12.00%
12.00%
Peer Group Rtn. (NAV)
12.00%
12.00%
12.00%
12.00%
12.00%
12.00%
12.00%
12.00%
% Rank in Peer Group (NAV)
5.0
5.0
5.0
5.0
5.0
5.0
5.0
5.0
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Annual Total Returns Versus Peers

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Name
2018
2019
2020
2021
2022
2023
2024
YTD
3.96%
28.74%
25.09%
6.41%
-3.06%
7.10%
3.21%
-6.63%
-8.71%
27.67%
15.90%
21.82%
-18.14%
23.79%
18.67%
3.71%
7.94%
25.25%
19.43%
11.74%
-5.96%
3.53%
3.78%
-4.30%
5.81%
25.64%
12.73%
21.83%
-9.72%
5.43%
3.21%
-3.32%
3.52%
22.30%
15.43%
15.34%
-7.22%
5.44%
3.63%
-4.41%
-1.37%
29.30%
15.05%
18.54%
-5.43%
8.22%
0.52%
-4.65%
As of May 14, 2025.

Fundamentals

General
Distribution Yield --
Dividend Yield TTM (5-13-25) 0.00%
30-Day SEC Yield --
7-Day SEC Yield --
Stock
Weighted Average PE Ratio 39.11
Weighted Average Price to Sales Ratio 10.31
Weighted Average Price to Book Ratio 9.410
Weighted Median ROE 11.83%
Weighted Median ROA -2.98%
ROI (TTM) -1.25%
Return on Investment (TTM) -1.25%
Earning Yield 0.0308
LT Debt / Shareholders Equity 1.694
As of December 31, 2024

Growth Metrics

EPS Growth (1Y) 10.70%
EPS Growth (3Y) 4.61%
EPS Growth (5Y) 9.67%
Sales Growth (1Y) 14.75%
Sales Growth (3Y) 16.77%
Sales Growth (5Y) 16.51%
Sales per Share Growth (1Y) 21.11%
Sales per Share Growth (3Y) 20.24%
Operating Cash Flow - Growth Ratge (3Y) 6.63%
As of December 31, 2024

Asset Allocation

Created with Highcharts 11.1.0
As of December 31, 2024.
Type % Net
Cash 0.00%
Stock 99.43%
Bond 0.00%
Convertible 0.00%
Preferred 0.21%
Other 0.36%
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Top 10 Holdings

Created with Highcharts 11.1.0
Name % Weight Price % Change
Eli Lilly and Co 9.39% 715.65 -4.08%
UnitedHealth Group Inc 6.87% 308.10 -1.05%
AstraZeneca PLC 4.01% 135.36 0.00%
Johnson & Johnson 3.59% 146.16 -1.54%
Boston Scientific Corp 3.13% 102.93 -0.02%
Abbott Laboratories 3.09% 128.48 -0.44%
Sanofi SA 3.05% 102.43 -3.30%
Amgen Inc 2.89% 262.22 -3.04%
AbbVie Inc 2.82% 177.07 -5.81%
Vertex Pharmaceuticals Inc 2.81% 420.86 -2.58%

Fees & Availability

Fees
Actual 12B-1 Fee 0.25%
Actual Management Fee 0.64%
Administration Fee --
Maximum Front Load --
Maximum Deferred Load --
Maximum Redemption Fee 0.00%
General Availability
Available for Insurance Product --
Available for RRSP --
Purchase Details
Open to New Investors Yes
Minimum Initial Investment 2500.00 None
Minimum Subsequent Investment 0.00 None

Basic Info

Investment Strategy
The Fund seeks long-term growth of capital. The Fund invests, under normal circumstances, at least 80% of its net assets in securities of companies that the portfolio managers believe have a life science orientation. The Fund normally invests in issuers from several different countries, which may include United States.
General
Security Type Mutual Fund
Broad Asset Class Sector Equity
Broad Category Equity
Global Peer Group Equity Sector Healthcare
Peer Group Global Health/Biotechnology Funds
Global Macro Equity Industry Sector
US Macro World Sector Equity Funds
YCharts Categorization --
YCharts Benchmark --
Prospectus Objective Global Health/Biotechnology Funds
Fund Owner Firm Name Janus Henderson Investors
Broad Asset Class Benchmark Index
^MSWNTR 100.0%

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Fundamentals

General
Distribution Yield --
Dividend Yield TTM (5-13-25) 0.00%
30-Day SEC Yield --
7-Day SEC Yield --
Stock
Weighted Average PE Ratio 39.11
Weighted Average Price to Sales Ratio 10.31
Weighted Average Price to Book Ratio 9.410
Weighted Median ROE 11.83%
Weighted Median ROA -2.98%
ROI (TTM) -1.25%
Return on Investment (TTM) -1.25%
Earning Yield 0.0308
LT Debt / Shareholders Equity 1.694
As of December 31, 2024

Growth Metrics

EPS Growth (1Y) 10.70%
EPS Growth (3Y) 4.61%
EPS Growth (5Y) 9.67%
Sales Growth (1Y) 14.75%
Sales Growth (3Y) 16.77%
Sales Growth (5Y) 16.51%
Sales per Share Growth (1Y) 21.11%
Sales per Share Growth (3Y) 20.24%
Operating Cash Flow - Growth Ratge (3Y) 6.63%
As of December 31, 2024

Fund Details

Key Dates
Inception Date 12/31/1998
Last Annual Report Date 9/30/2024
Last Prospectus Date 1/28/2025
Share Classes
JAGLX T
JFNAX A
JFNCX C
JFNIX Inst
JFNNX N
JNGLX D
Attributes
Index Fund --
Inverse Fund --
Leveraged Fund --
Fund of Funds No
Currency Hedged Fund --
Synthetic Replication Fund No

Top Portfolio Holders

Name % Weight
Portfolio A 5.00%
Portfolio B 3.50%
Portfolio C 2.25%
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Excel Add-In Codes

Name: =YCI("M:JFNSX", "name")
Broad Asset Class: =YCI("M:JFNSX", "broad_asset_class")
Broad Category: =YCI("M:JFNSX", "broad_category_group")
Prospectus Objective: =YCI("M:JFNSX", "prospectus_objective")
To find the codes for any of our securities and financial metrics, see our Complete Excel Reference.
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